GGT

Gamma-glutamyltransferase (GGT) is an enzyme that plays a crucial role in the metabolism of glutathione and the transfer of amino acids across the cellular membrane. It is predominantly found in the liver, kidney, and pancreas. Clinically, GGT is used as a biomarker for liver function and is sensitive to alcohol consumption, liver inflammation, and bile duct obstruction. Researchers have found that elevated GGT levels are associated with chronic alcohol use, liver disease, and cardiovascular risk. In athletic performance and biohacking contexts, GGT may be considered for its role in oxidative stress and metabolic syndrome, though its direct impact on performance is less clear. Caveats include potential confounders such as age, gender, obesity, and alcohol intake. Time-of-day and fasting status do not significantly affect GGT levels, but recent alcohol consumption can elevate results, necessitating careful interpretation.