Glutathion

Glutathione (GSH), also known as reduced glutathione, is a tripeptide composed of glutamine, cysteine, and glycine. It serves as a major antioxidant in the body, participating in cellular redox reactions and detoxifying xenobiotics. GSH is crucial for maintaining redox balance, protecting cells from oxidative damage, and supporting immune function. Researchers have found that GSH levels reflect the body's ability to counteract oxidative stress and maintain cellular health. Clinically, GSH is significant in conditions characterized by oxidative stress, such as schizophrenia, severe community-acquired pneumonia, and various neurological disorders. Altered GSH levels are associated with disease progression and prognosis, making it a potential biomarker for these conditions. In the context of longevity and biohacking, GSH is valued for its role in reducing oxidative stress and supporting detoxification processes, which are believed to contribute to improved healthspan and reduced age-related decline. Athletes and biohackers often seek to optimize GSH levels to enhance recovery and immune function. However, GSH levels can be influenced by factors such as diet, supplementation, and overall health status. Researchers observed that oral supplementation can increase GSH levels, but the bioavailability and long-term effects in humans require further study. Testing for GSH does not typically require fasting, but levels may vary with time of day and other physiological factors.