Lifestyle
- Regular moderate exercise
- Adequate sleep
- Stress management
White Blood Cells · WBC · Weiße Blutkörperchen
The WBC test quantifies the number of white blood cells in a given volume of blood, reflecting immune system activity.
Reference ranges can vary slightly depending on the laboratory and population.
White blood cells (WBCs), also known as leukocytes, are a critical component of the immune system, responsible for defending the body against infectious disease and foreign invaders. They are produced in the bone marrow and circulate throughout the bloodstream and lymphatic system. WBCs are categorized into different types, including lymphocytes, monocytes, and granulocytes, each playing distinct roles in immune response. Clinically, WBC count is a vital marker in diagnosing and monitoring various conditions. Elevated WBC levels can indicate infections, inflammation, stress, or hematologic malignancies, while low levels may suggest bone marrow disorders, autoimmune diseases, or the effects of certain medications. In the context of athletic performance and biohacking, maintaining an optimal WBC count is crucial for recovery and overall health, as it reflects the body's ability to respond to physical stress and potential pathogens. However, WBC counts can be influenced by various factors, including time of day, recent physical activity, and medications such as warfarin, which has been shown to modestly reduce WBC counts. Therefore, it is important to consider these factors when interpreting WBC results.
Klinische Bedeutung
Elevated WBC counts may indicate infections, inflammation, or stress, while low counts can suggest bone marrow disorders or the effects of medications like warfarin.
Progressively rising WBC counts may indicate worsening infection or inflammation. Re-test in 1-2 weeks if elevated.
Falling WBC counts could suggest resolving infection or potential bone marrow suppression.
Re-test Interval
4 weeks if outside optimal range
Note:
Consult a healthcare provider before making significant lifestyle or dietary changes.
WBC counts can vary throughout the day; morning samples are preferred for consistency.
Testing Frequency
Annually for healthy adults, more frequently if monitoring a condition.
Current research suggests that the effects of warfarin on white blood cell (WBC) counts, particularly granulocytes, remain understudied, with reference ranges and optimal targets not clearly defined. Researchers have not yet established the long-term implications of altered WBC counts in various clinical contexts, such as osteoarthritis and congenital myasthenic syndrome. Unanswered clinical questions include the precise role of elevated neutrophil counts in disease protection and the impact of acute stressors on WBC dynamics.
574
Total Citations
25
Human/RCT
2.1
Avg. Influence
2025
Latest
This research examined DNA methylation in white blood cells (WBC) as a potential biomarker for various health outcomes. Researchers noted associations between global WBC methylation and several cancers, highlighting the need for further studies to clarify these relationships.
This study examined the use of digital image analysis for counting various blood cells, including white blood cells (WBCs). Researchers found that while automated microscopy can provide accurate WBC differential counts, manual microscopy remains essential for confirming abnormal findings.
This study examined hypoxemia during hemodialysis in mechanically ventilated patients. Researchers found significant decreases in white blood cell (WBC) counts, suggesting that leuko-agglutination may contribute to hypoxemia during the procedure.
Researchers reviewed the prevalence of leukocytosis in rheumatoid arthritis (RA) patients. They found that 27% of patients had elevated white blood cell (WBC) counts, primarily due to increased neutrophils, and suggested that leukocytosis may indicate more active disease.
Researchers investigated the relationship between white blood cell (WBC) and platelet counts with hepatic steatosis in a large cohort. They found significant associations between higher WBC counts and the severity of hepatic steatosis, suggesting that WBC counts may be useful in identifying at-risk individuals.
This study evaluated the role of white blood cell (WBC) and platelet counts in diagnosing dementia. Researchers found no significant differences in WBC counts between demented and non-demented patients, suggesting these are not suitable biomarkers.
This research aimed to develop reference values for blood parameters in Canary Island camels. Researchers reported a white blood cell (WBC) count range of 7.35 - 18.36 X103/µL, with variations based on age and sex.
This study assessed the impact of sleep deprivation on white blood cell (WBC) counts. Researchers found that WBC levels were negatively correlated with sleep efficiency, with increased granulocyte counts observed after sleep deprivation.
Researchers studied cytokine expression in white blood cells (WBC) of patients with small fiber neuropathy (SFN). They found higher levels of pro-inflammatory cytokines IL-2, IL-8, and TNF in patients compared to healthy controls, indicating potential diagnostic relevance.
This clinical study assessed fibulin-2 as a potential biomarker for early infection diagnosis. Researchers found that fibulin-2 levels were elevated in infected patients compared to non-infected individuals, outperforming traditional biomarkers like WBC in diagnostic ability.
Research publications about Leukozyten over time
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