Lifestyle
- Regular monitoring of vitamin A intake
- Avoid excessive alcohol consumption
Retinol · Vitamin A · Retinyl Palmitate
Vitamin A tests measure the concentration of retinol in the blood, reflecting the body's vitamin A status.
Reference ranges may vary slightly based on age and laboratory standards.
Vitamin A, also known as retinol, is a fat-soluble vitamin essential for various biological functions, including vision, immune function, and cellular communication. It exists in several forms, with retinol being the most biologically active. Retinoic acid, a derivative of vitamin A, plays a crucial role in gene expression and cellular differentiation. Vitamin A can be obtained from animal-derived foods as retinol or from plant-based foods as provitamin A carotenoids, which are converted into retinol in the body. Clinically, vitamin A is significant for maintaining healthy vision, skin, and immune function. Deficiency can lead to conditions such as night blindness and increased susceptibility to infections, while excess intake may result in toxicity, characterized by symptoms like liver damage and central nervous system disorders. In the context of athletic performance and biohacking, vitamin A is crucial for maintaining optimal vision and immune function, which can indirectly influence performance and recovery. However, excessive supplementation without medical supervision can lead to toxicity. Researchers have found that vitamin A levels can be influenced by factors such as dietary intake, liver function, and genetic variations. Testing for vitamin A levels typically does not require fasting, but it is important to consider potential confounders such as recent dietary intake and liver health when interpreting results.
Klinische Bedeutung
Elevated vitamin A levels may indicate excessive supplementation or liver disease, while low levels suggest dietary deficiency or malabsorption issues. Both extremes can lead to significant health problems.
Progressively rising values may suggest excessive supplementation or liver dysfunction. Re-test in 4 weeks if outside optimal range.
Progressively falling values may indicate dietary deficiency or malabsorption.
Re-test Interval
4 weeks if outside optimal range
Note:
Consult a healthcare provider before starting supplements, especially if you have liver disease.
Testing Frequency
Annually for those at risk of deficiency or excess.
Correlated with
Current research suggests that the relationship between vitamin A levels and type 2 diabetes remains uncertain, particularly regarding optimal targets and reference ranges for vitamin A in metabolic contexts. Researchers have not yet established the confounding factors that influence vitamin A metabolism in diabetic patients. Additionally, clinical questions remain unanswered regarding the efficacy of retinoids in treating colorectal cancer, especially in cases where retinoic acid receptor expression is lost.
2,283
Total Citations
9
Human/RCT
5.1
Avg. Influence
2025
Latest
Researchers highlighted the ongoing public health issue of measles and its complications, particularly in the context of vitamin A deficiency. The study found that vitamin A deficiency can exacerbate the severity of measles complications, especially in malnourished children.
This review highlighted the immunomodulatory effects of beta-carotene, a precursor to vitamin A, in enhancing immune responses and potentially reducing tumor burden in animal studies. Researchers noted that while vitamin A itself is a poor antioxidant, beta-carotene may play a more significant role in health.
Researchers provided a historical overview of vitamin A deficiency and its clinical manifestations. They noted that symptoms range from eye-related issues to growth disturbances and increased infection susceptibility. The study highlighted the evolution of understanding vitamin A deficiency and its global health implications.
This review discussed methods for assessing vitamin A status, noting that traditional classifications are evolving. Researchers found that serum retinol concentrations are homeostatically controlled and may not reflect deficiency until liver reserves are low. The study emphasizes the importance of using multiple assessment methods to accurately evaluate vitamin A status.
Researchers reviewed the relationship between vitamin A deficiency and cancer, establishing a link between retinoids and tumor prevention. The study emphasized the need for continued research on retinoid signaling pathways for therapeutic applications.
This review addressed global efforts to control vitamin A deficiency disorders (VADD), which affect millions. Researchers noted that while progress has been made through supplementation and food fortification, sustainable strategies are essential for long-term success.
This study characterized vitamin A deficiency in Australian children, finding a prevalence of 35.6% among those assessed. Researchers observed significant associations between vitamin A deficiency and conditions such as anemia and systemic health issues, indicating a need for ophthalmic review.
This study reviewed the potential of lipophilic antioxidants, including vitamin A, in neurodegenerative diseases. Researchers found that while there is no clear clinical evidence of benefit, some studies suggest that these antioxidants may provide neuroprotection in cellular and animal models.
This review examined the complex relationship between vitamin A and bone health, noting that high intake of preformed vitamin A may increase osteoporosis risk. Researchers found that carotenoids, vitamin A precursors, are associated with better bone health. The study calls for further research to clarify the impact of different forms of vitamin A on bone health.
In a study involving healthy adults exposed to norovirus, researchers observed that inflammation affected serum concentrations of several micronutrient biomarkers, including vitamin A. Specifically, retinol levels were found to be depressed during the inflammatory response following infection.
2
Total Trials
100,027
Total Enrolled
First Affiliated Hospital of Zhejiang University
100,000
2024
serum vitamin A
University of Wisconsin, Madison
27
2012
Serum retinyl esters, nmol/L
Research publications about Vitamin A over time
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